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Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL)

Abteilung Mikrobiologie
Technische Universität München
Weihenstephaner Berg 3
D-85350 Freising

PD Dr. Klaus Neuhaus, Biologist
 
 
Phone: +49-8161-71 5549
E-mail: neuhaus@wzw.tum.de
 
 
Research and professional career
 
 
publication list 

Fellner L, Huptas C, Simon S, Mühlig A, Scherer S, Neuhaus K (2016) Draft genome sequences of three European laboratory derivatives from enterohemmorrhagic Escherichia. coli  O157:H7 strain EDL933, including two plasmids.Genome Announcements 4(2):e01331-15

Neuhaus K, Landstorfer R, Fellner L, Simon S, Schafferhans A, Goldberg T, Marx H, Ozoline ON, Rost B, Kuster B, Keim DA, Scherer S (2016) Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC). BMC Genomics 17:133

Fellner L, Simon S, Scherling C, Witting M, Schober S, Polte C, Schmitt-Kopplin P, Keim DA, Scherer S, Neuhaus K (2015) Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting. BMC Evol Biol. 15:283 

Simon S, Mittelstädt S, Kwon BC, Stoffel A, Landstorfer R, Neuhaus K, Mühlig A, Scherer S, Keim DA (2015) VisExpress: Visual exploration of differential gene expression data. Info Vis, 
14:1473871615612883

Landstorfer R, Simon S, Schober S, Keim D, Scherer S, Neuhaus K (2014) Comparison of strand-specific transcriptomes of enterohemorrhagic Escherichia coli O157:H7 EDL933 (EHEC) under eleven different environmental conditions including radish sprouts and cattle feces. BMC Genomics 15:353

Fellner L, Bechtel N, Witting MA, Simon S, Schmitt-Kopplin P, Keim D, Scherer S, Neuhaus K (2014) Phenotype of htgA (mbiA), a recently evolved orphan gene of Escherichia coli and Shigella, completely overlapping in antisense to yaaW. FEMS Microbiol Lett 350:57-64

Mir K, Neuhaus K, Bossert M, Schober S (2013) Short Barcode for Next Generation Sequencing. PLoS ONE 8(12):e82933 

Neuhaus K, Satorhelyi P, Schauer K, Scherer S, Fuchs TM (2013) Acid shock of Listeria monocytogenes at low environmental temperatures induces prfA, epithelial cell invasion, and lethality towards Caenorhabditis elegans. BMC Genomics, 14:285.

Lang Halter E, Neuhaus K, Scherer S (2013) Listeria weihenstephanensis sp.nov., isolated from the water plant Lemna trisulca of a German fresh water pond. Int. J. Syst. Evol. Microbiol., 63(2):641–647. 

Fuchs T, Neuhaus K, Scherer S (2013) Life at Low Temperatures. In: M. Dworkin et al., eds., The Prokaryotes,  Springer Verlag, Berlin Heidelberg.

Schober S, Mir K, Neuhaus K, Bossert M (2012) Design of Short Barcodes for Next Generation Sequencing of DNA and RNA. In: IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), pp. 31–34, Washington DC, USA, doi:10.1109/GENSIPS.2012.6507719.

Mir K, Neuhaus K, Scherer S, Bossert M, Schober S (2012) Predicting statistical properties of open reading frames in bacterial genomes. PLoS ONE 7(9):e45103. 

Simon S, Oelke D, Landstorfer R, Neuhaus K, Keim D (2011) Visual Analysis of Next-Generation Sequencing Data to Detect Overlapping Genes. In:  IEEE Symposium on Biological Data Visualization, pp. 47–54, Providence, Rhode Island, USA.

Oelke D, Janetzko H, Simon, S, Neuhaus K, Keim DA (2011) Visual Boosting in Pixel-based Visualizations. Comput Graph Forum 30:871-880.

Samelis J, Bleicher A, Delbès-Paus C, Kakouri A, Neuhaus K, Montel M-C (2010) FTIR-based polyphasic identification of lactic acid bacteria isolated from traditional Greek Graviera cheese. Food Microbiol., 28(1):76-83. 

Bleicher A, Stark T, Hofmann T, Bogovic Matijasic B, Rogelj I, Scherer S, Neuhaus K (2010) Potent antilisterial cell-free supernatants produced by complex red smear cheese microbial consortia. J. Dairy Sci., 93(10):4497-4505.

Bleicher A, Obermajer T, Bogovic Matijasic B, Scherer S, Neuhaus K (2010) High biodiversity and potent anti-listerial action of complex red smear cheese microbial ripening consortia. Ann. Microbiol., 60(3):531-539.

Neuhaus K, Oelke D, Fürst D, Scherer S, Keim DA (2010) Towards automatic detecting of overlapping genes - Clustered BLAST analysis of viral genomes.  Lect. Notes Comput. Sci. 6023:228–239.

Bleicher A, Neuhaus K, Scherer S (2010) Vibrio casei sp. nov., isolated from the surface of two French red smear soft cheeses. Int.J. Syst. Evol. Microbiol 60(Pt.8):1745-1749 

Monnet C, Bleicher A, Neuhaus K, Sarthou A-S, Leclercq-Perlat M-N, Irlinger F (2009) Assessment of the anti-listerial activity of microfloras from the surface of smear-ripened cheeses. Food Microbiol. 27(2): 302-3010


Hain T, Chatterjee SS, Ghai R, Kuenne CT, Billion A, Steinweg C, Domann E, Kärst U, Jänsch L, Wehland J, Eisenreich W, Bacher A, Joseph B, Schär J, Kreft J, Klumpp J, Loessner MJ, Dorscht J, Neuhaus K, Fuchs TM, Scherer S, Doumith M, Jacquet C, Martin P, Cossart P, Rusniock C, Glaser P, Buchrieser C, Goebel W, Chakraborty T. (2007) Pathogenomics of Listeria spp. Int. J. Medical Microbiol. 297, 541-557.

Jakob K, Satorhelyi P, Lange C, Wendisch VF, Silakowski B, Scherer S, Neuhaus K (2007) Gene expression analysis of long-term lactic acid adapted Corynebacterium glutamicum. J.Bacteriol, J. Bacteriol. 189, 5582-5590.
 

Loessner H, Endmann A, Leschner S, Westphal K, Rohde M, Miloud T, Hämmerling G, Neuhaus K, Weiss S (2007) Remote control of tumor targeted Salmonella enterica serovar Typhimurium - L-arabinose as inducer of bacterial gene expression in vivo. Cell. Microbiol. 9, 1529-1537.

Keim DA, Oelke D, Truman R, Neuhaus K (2006) Finding correlations in functionally equivalent proteins by integrating automated and visual data exploration. Proc. Sixth IEEE Symp. BioInformatics BioEngineering 0, 183-192.


Bresolin G, Neuhaus K, Scherer S, Fuchs TM (2006) Transcriptional analysis of long-term adaptation of Yersinia enterocolitica to low-temperature growth.J. Bacteriol. 188, 2945-2958.


Scherer S,
Neuhaus K (2006) Life at low temperatures. in Dworkin M, Falkow S, Rosenberg E, Schleifer KH, Stackebrandt E, eds., The Prokaryotes: A Handbook on the Biology of Bacteria. Vol. 2: Ecophysiology and Biochemistry, 3rd edition, October 6, 2006, Springer-Verlag, New York. 

Neuhaus K
, Anastasov N, Kaberdin V, Francis KP, Miller VL, Scherer S (2003) The AGUAAA motif in cspA1/A2 mRNA is important for adaptation of Yersinia enterocolitica to grow at low temperature. Mol. Microbiol. 50, 1629-1645.
 
Maoz A, Mayr R, Bresolin G, Neuhaus K, Francis KP, Scherer S (2002) Sensitive in situ monitoring of a recombinant bioluminescent Yersinia enterocolitica reporter mutant in real time on Camembert cheese. Appl. Environ. Microbiol. 68, 5737-5740.
 
Neuhaus K, Rapposch S, Francis KP, Scherer S (2000) Restart of exponential growth of cold-shocked Yersinia enterocolitica occurs after down-regulation of cspA1/A2 mRNA. J. Bacteriol. 182, 3285-3288.
 
Neuhaus K, Grsic-Rausch S, Sauerteig S, Ludwig-Müller J (2000) Arabidopsis plants transformed with nitrilase 1 or 2 in antisense direction are delayed in clubroot development. J. Plant Phys. 156, 756-761.
 
Neuhaus K (2000) Characterization of major cold shock protein genes of the psychrotolerant food pathogens Bacillus weihenstephanensis and Yersinia enterocolitica. Univ. Diss. Technische Universität München; Hieronymus, München, ISBN 3-89791-124-8.
 
Neuhaus K Francis KP, Rapposch S, Görg A, Scherer S (1999) Pathogenic Yersinia species carry a novel, cold-inducible major cold shock protein tandem gene duplication producing both bicistronic and monocistronic mRNA. J. Bacteriol. 181, 6449-6455.
 
von Stetten F, Francis KP, Lechner S, Neuhaus-K, Scherer S (1998) Rapid discrimination of psychrotolerant and mesophilic strains of the Bacillus cereus group by PCR targeting of 16S rDNA. J. Microbiol. Methods 34, 99-106.
 
Grsic S, Sauerteig S, Neuhaus K, Albrecht M, Rossiter J, Ludwig-Müller J (1998). Physiological analysis of transgenic Arabidopsis thaliana plants expressing one nitrilase isoform in sense or antisense direction. J. Plant Physiol. 153, 446-456.
 
 
 
 
 
 
 
 

Aktuelles

Forschungspreis
Otto-von-Guericke Forschungspreis für Siegfried Scherer

Preisverleihung
Innovationspreis für Siegfried Scherer

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Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk Is Mainly Induced by Psychrotolerant Spore-Forming Bacteria that often Originate from Recontamination

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Berufung Expertenrat
Prof. Dr. Siegfried Scherer wurde in den Expertenrat für Lebensmittelsicherheit des Bayerischen Staatsministeriums für Umwelt und Verbraucherschutz berufen.

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Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC)

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A sensitive and robust method for direct determination of lipolytic activity in natural milk environment (März 2016, online first)

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Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting (Dez. 2015).

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