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Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL)

Abteilung Mikrobiologie
Technische Universität München
Weihenstephaner Berg 3
D-85350 Freising

Taxonomy and evolution 
Prof.Dr. Siegfried Scherer

Our interest comprises the study of intra- and interspecific biodiversity of microbial communities, including the description of novel species. The focus is on foodborn bacteria. Our strain collection now includes some 7000 strains which serve as a reference for species description, and for the evaluation of phyolgenetic relationships within species or closely related species groups.

 A second focus is on the theoretical analysis of evolutionary processes. Especially, I am interested in evaluating microevolutionary processes with respect to their bearing on macroevolutionary transitions. What kind of microevolutionary changes can be observed? How far-reaching are they? How fast do they occur? What kind of biological information results from such changes? Are experimentally observable microevolutionary factors suitable to mechanistically explain macroevolutionary processes or do such changes require other factors?



Publications  "Taxonomy and evolution (selection)

 Mayr R, Busse HJ, Worliczek HL, Ehling-Schulz M, Scherer S (2006) Ornithinibacillus gen. nov., with the species Ornithinibacillus bavariensis sp. nov. and Ornithinibacillus californiensis sp. nov..International Journal of Systematic and Evolutionary Microbiology 56, 1383-1389.

 Ehling-Schulz M, Svensson B, Guinebretiere MH, Lindback T, Andersson M, Schulz A, Fricker M, Christiansson A, Granum PE, Martlbauer E Nyguyen-The C, Salkinoja-Salonen M and S. Scherer S (2005) Emetic toxin formation of Bacillus cereus is restricted to a single evolutionary lineage of closely related strains. Microbiology 151, 183-197.

 Loewe L, Textor V, Scherer S (2003) High deleterious genomic mutation rate in stationary phase of Escherichia coli. Science 302, 1558-1560.

 Scherer S, Junker R (2003) Evolution. In: Enzyklopädie Naturwissenschaft und Technik, 8. Ergänzungslieferung, Ecomed Verlagsgesellschaft, Landsberg/Lech, 1-10.

 Oberreuter H, Charzinski J, Scherer S  (2002) Intraspecific diversity of Brevibacterium linens, Corynebacterium glutamicum and Rhodococcus erythropolis based on partial 16S rDNA sequence analysis and Fourier-transform infrared (FT-IR) spectroscopy. Microbiology 148, 1523-1532.

 Oberreuter H, Seiler H, Scherer S (2002) Identification of coryneform bacteria and related taxa by Fourier-transformed infrared (FT-IR) spectroscopy. International Journal of Systematic and Evolutionary Microbiology 52: 91-100.

 Lechner S, Mayr R, Francis KP, Prüß B, Kaplan T, Wießner-Gunkel E, Stewart GSAB, Scherer S (1998) Bacillus weihenstephanensis sp.nov. is a new psychrotolerant species of the Bacillus cereus group. International Journal of Systematic and Evolutionary Microbiology 48, 1373-1382.

 Scherer S, Lechner S, Böger P (1993) psbD sequences of Bumilleriopsis filiformis (Heterokontophyta, Xanthophyceae) and Porphyridium purpureum (Rhodophyta, Bangiophycidae): evidence for polyphyletic origin of plastids. Current Genetics 24: 437-442. 

 Scherer S, Herrmann G, Hirschberg J, Böger P (1991) Evidence for multiple xenogenous origins of plastids: Comparison of psbA genes with a xanthophyte sequence. Current Genetics 19: 503-507.

 Scherer S (1990) The protein molecular clock: Time for a re-evaluation. Evolutionary Biology 24, 83-106.

 Scherer S (1989) The relative rate test of molecular evolution: A note of caution. Molecular Biology and Evolution 6, 436-441.

 Scherer S (1985) Could life have arisen in the primitive atmosphere? Journal of Molecular Evolution 22, 91-94.

 Scherer S (1983) Basic functional states in the evolution of cyclic photosynthetic electron transport. Journal of Theoretical Biology 104, 289-299.

 Scherer S, Hilsberg T (1982) Hybridisierungen und Verwandtschaftsgrade innerhalb der Anatidae: Eine evolutionstheoretische und systematische Betrachtung. Journal für Ornithologie 123,357-380.




Innovationspreis für Siegfried Scherer

Otto-von-Guericke Forschungspreis für Siegfried Scherer


Differentiation of ncRNAs from small mRNAs in Escherichia coli O157:H7 EDL933 (EHEC) by combined RNAseq and RIBOseq-ryhB encodes the regulatory RNA RyhB and a Peptide, RyhP. (2017)

Complete circular genome sequence and temperature independent adaptation to Anaerobiosis of Listeria weihenstephanensis DSM 24698 (2017)

Discovery of numerous novel small genes in the intergenic regions of the Escherichia coli O157:H7 Sakai Genome (2017)

High binding affinity of repressor IolR avoids costs of untimely induction of myo-inositol utilization by Salmonella Typhimurium (2017)

Genetic characterization of the Galactitol utilization pathway of Salmonella enterica serovar Typhimurium. (2017)

Heat stability of indigenous milk plasmin and peptidases from Pseudomonas: a challenge in the production of ultra-high temperature milk products (2016)

Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk Is Mainly Induced by Psychrotolerant Spore-Forming Bacteria that often Originate from Recontamination (2017)

Bakterieller Stoffwechsel als Pathogenitätsfaktor (2016)

Transcriptional and translational regulation by RNA thermometers, riboswitches and the sRNA DsrA in Escherichia coli O157:H7 Sakai under combined cold and osmotic stress adaptation. (2016)

Hysteresis in myo-inositol utilization by Salmonella Typhimurium (2016)

Probiotic Enterococcus faecalis Symbioflor® down regulates virulence genes of EHEC in vitro and decrease pathogenicity in a Caenorhabditis elegans model (2017)

Draft Genome Sequence of Lysinibacillus xylanilyticus SR-86 (Nov. 2016)

Permanent colonization of creek sediments, creek water and limnic water plants by four Listeria species in low population densities (November 2016)

Draft Genome Sequence of the Xanthan Producer Xanthomonas campestris LMG 8031 (Oktober 2016)

Comparative Bioinformatics and Experimental Analysis of the Intergenic Regulatory Regions of Bacillus cereus hbl and nhe Enterotoxin Operons and the Impact of CodY on Virulence Heterogeneity (Mai 2016)

Regulation of fucose and 1,2-propanediol utilization by Salmonella enterica serovar Typhimurium (März 2016)

Acidified nitrite inhibits proliferation of Listeria monocytogenes - Transcriptional analysis of a preservation method (März 2016)

Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC)

A sensitive and robust method for direct determination of lipolytic activity in natural milk environment (März 2016, online first)

Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting (Dez. 2015)

Massive horizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe (Nov. 2015)

Chemodiversity of cereulide, the emetic Toxin of Bacillus cereus (2015)