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Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL)

Abteilung Mikrobiologie
Technische Universität München
Weihenstephaner Berg 3
D-85350 Freising








Dr. Zachary Ardern

Biologist
Postdoctoral Researcher

Phone: +49 (8161) 71 3945
Fax: +49 (8161) 71 4492
E-Mail: zachary.ardern @ tum.de

CV
 

  • since 2016 Postdoctoral researcher, at the chair in Microbial Ecology, at ZIEL, Technical University of Munich, Research topic: "Genomic features impacting the prevalence and evolutionary history of overlapping genes in bacteria"
  • 2013 - 2016 PhD in Biological Sciences at the University of Auckland, New Zealand. Thesis title "Small Change? Adaptation and ist costs, in experimental evolution"
  • 2012 Postgraduate Diploma in Biological Sciences at the University of Auckland, endorsed with Merit. Emphasis in molecular biology.
  • 2008 - 2012 Bachelor of Arts / Bachelor of Science conjoint degrees, majoring in Economics, Philosophy and Biology - the University of Auckland, New Zealand


























Katharina Springer geb. Brauer

Biologist
PhD student

Phone: +49 (81 61) 71 5091
Fax: +49 (81 61) 71 4492
E-Mail: katharina.brauer @ wzw.tum.de  


CV

 
  • since June 2014: Phd Student at the TU Munich, Department of Microbiology, ZIEL, in the Research Group of Prof. Dr. Thilo Fuchs, working on "Regulation and function of insecticidal genes of Yersinia enterocolitica"
  • June 2013 - December 2014: Master´s Thesis at the Bundeswehr Institut of Microbiology (Munich Neuherberg) in the Department of Virology and Rickettsiology with the titel: "Establisment of cell death specific PCR Arrays for the Investigation of tick-borne encephalitis virus strains in three different cell lines"
  • October 2008 - January 2014: Studies in Biology at the Technical University of Munich


























Dettling Anna


PhD Student

Phone: +49 (81 61) 71 3859
Fax: +49 (81 61) 71 4492
E-Mail: Anna.dettling@tum.de


CV

 


  • since June 2016: PhD Student at the Department of Microbial Ecology, ZIEL TU Munich in the group of Dr. Mareike Wenning. Research topic: "Thermophile spore forming bacteria in milk and dairy products"
  • 2013-2016: Studies in Food Microbiology and Biotechnology at the Hohenheim University
  • 03/2016 Master´s Thesis at the Department of Soft Matter Science and Dairy Technology, Hohenheim University. Research topic: "Thermophile spore forming bacteria in milk systems: Instrumental design, heat restistance and growth"
  • 2009-2012 Studies in Biotechnology at the Jena Ernst-Abbe-University of Applied Sciences



























Dr. Etienne Doll

Nutritionist
Postdoctoral Researcher

Phone: +49 (8161) 71 5570
Fax: +49 (8161) 71 4492 
E-mail:
etienne.doll @ tum.de                                

CV
 

  • since 01/2018 Postdoctoral scientist, Consulting and Analytical Service for microbiological production problems in the food industry, Chair of Microbial Ecology, ZIEL, TU München
  • 01/2018 Doctoral degree on "Microbiota of extended shelf life milk - Population dynamics during processing and cold storage"
  • 09/2017 - 12/2017 Visiting scholar in the research group of Prof. Dr. Martin Wiedmann, Food Safety Laboratory, Cornell University on "Stress adaptation and virulence in Listeria monocytogenes "
  • 12/2013 - 09/2017 PhD student in the research group of Dr. Mareike Wenning at the Chair of Microbial Ecology, ZIEL, TU München.
  • 03/2010 - 10/2013 Master´s Thesis in the research group of Dr. Mareike Wenning. Chair  of Microbial Ecology, ZIEL, TU München. Research topic: "Detailed analysis of raw milk microbiota".
  • 10/2008 - 11/2013 Studies in Nutritional Science, TU München

List of publications

Doll, E.V, Scherer, S, Wenning, M. (2017) Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk is Mainly Induced by Psychrotolerant spore-Forming Bacteria that often originate from Recontamination. Frontiers in Microbiology, 8


























   
Glaub Alina

PhD Student

Phone: +49 (8161) 71 3945 
Fax: +49 (8161) 71 4492 
E-mail: Alina.glaub
@ tum.de                                

CV
 

  • since March 2018 PhD Student at the Department of Microbial Ecology, ZIEL TU Munich
  • 06/2015 - 02/2018  Scientific assistant at the Department of human genetics, University clinic Münster, Germany
  • 2013 - 2016 Master degree in molecular biomedicine, Westfälische Wilhelms University Münster, Germany. Master thesis "Analysis of genetic diversity in the coding tegion of two genes involved in the phase-II-metabolism of tetrahydrocannabinol (THC)"
  • 2010 - 2013 Bachelor degree in biology, University Bielefeld, Germany. Bachelor Thesis: "Whole Genome-sequencing and annotation of Corynobacterium auriscanis and C.falsenii to identify potential virulence factors"
























Christopher Huptas

Biologist
PhD student

Phone:  +49 8161 71 5570
Fax:  +49 8161 71 4492
E-mail: christopher.huptas @ wzw.tum.de


CV
     

  • since 2012 PhD position at Lehrstuhl für mikrobielle Ökologie in the research group of Dr. Mareike Wenning, TU München. Research topic: "Characterisation of bacterial species on the basic of genomic sequences"
  • 2012 Master thesis at Lehrstuhl für mikrobielle Ökologie (Prof. Scherer), TU München, Research topic: "Characterisation of the genetic locus of the cereulide-synthetase gene cluster in emetic Bacillus weihenstephanensis MC67"
  • 2008 - 2012 Studies in biology at TU München
  • 2008 Bachelor thesis at Lehrstuhl für genomorientierte Bioinformatik (Prof. Fishman), TU München. Research topic: "Human polymorphisms at predicted microRNA target sites"
  • 2004 - 2008 Studies in bioinformatics at Ludwig-Maximilians-Universität und TU München
  • 2004 University-entrance diploma at Adolf-Weber-Gymnasium München






















































Dr. Genia Lücking
Biologist 

Phone +49 (81 61) 71 55 70
Fax + 49 (81 61) 71 44 92
E-mail: genia.luecking @ wzw.tum.de                  

 


Research career


  • since 2009 Postdoc scientist at the Unit of Microbiology, ZIEl, TU München
  • 2005 - 2009 PhD at the Unit of Microbiology, ZIEL, TU München: "Molecular characterization of cereulide synthesis in emetic Bacillus cereus"
  • 2004 Diploma thesis at the Department of Microbiology, Julius-Maximilian-University Würzburg: "Characterization of putative virulence factors in Bordetella holmseii
  • 1999-2004 studies in biology at the Julius-Maximilian-University Würzburg

Publikationen

Lücking G, Frenzel E, Rütschle A, Marxen S, Stark TD, Hofmann T, Scherer S, Ehling-Schulz M (2015) Ces locus embedded proteins control the non-ribosomal Synthesis of the cereulide Toxin in emetic Bacilluc cereus on multiple levels. Frontiers in Microbiologie 6:1101. doi:10.3389/fmicb.2015.01101.

Marxen S, Stark T, Rütschle A, Lücking G, Frenzel E, Scherer S, Ehling-Schulz M, Hofmann T (2015) Multiparametric Quantitation of the Bacillus cereus Toxins Cereulide and Isocereulides A-G in Foods. Journal of Agricultural and Food Chemistry 63(37):8307-13. doi:10.1021/acs.jafc.5b03705

Marxen S, Stark TD, Rütschle A, Lücking G, Frenzel E, Scherer S, Ehling-Schulz M, Hofmann T (2015) Depsipeptide Intermediates Interrogate Proposed Biosynthesis of Cereulide, the Emtic Toxin in Bacillus cereus. Sci Rep. 5:10637. doi:10.1038/srep10637

Marxen S, Stark TD, Frenzel E, Rütschle A, Lücking G, Pürstinger G, Pohl EE, Scherer S, Ehling-Schulz, M, Hofmann T (2015) Chemodiversity of cereulide, the emetic toxin of Bacillus cereus. Anal Bioanal Chem 407(9):2439-53. doi:10.1007/s00216-015-8511-y

Lücking G, Stoeckel M, Atamer Z, Hinrichs J, Ehling-Schulz M (2013)
Characterization of aerobic spore-forming bacteria associated with industrial dairy processing environments and product spoilage. Int J Food Microbiol166:270-279.

Stark, T., Marxen, S., Rütschle, A., Lücking, G., Scherer, S., Ehling-Schulz, M., Hofmann, T. (2013) Mass spectrometric profiling of Bacillus cereus strains and quantitation of the emetic toxin cereulide by means of stable isotope dilution analysis and HEp-2 bioassay. Analytical and bioanalytical chemistry 405:191-201. 


Frenzel, E., Doll, V., Pauthner, M., Lücking, G., Scherer, S., Ehling-Schulz, M. (2012) CodY orchestrates the expression of virulence determinants in emetic Bacillus cereus by impacting key regulatory circuits. Molecular microbiology 85:67-88. 

Witthuhn, M., Lücking, G., Atamer, Z., Ehling-Schulz, M., Hinrichs J. (2011) Thermal resistance of aerobic spore formers isolated from food products. International Journal of Dairy Technology 64:486-493. 

Dommel, M.K., Lücking, G., Scherer, S., Ehling-Schulz, M. (2011) Transcriptional kinetic analyses of  cereulide synthetase genes with respect to growth, sporulation and emetic toxin production in Bacillus cereus. Food microbiology 28:284-290. 

Lücking, G., Dommel, M.K., Scherer, S., Fouet, A., Ehling-Schulz, M. (2009) Cereulide synthesis in emetic Bacillus cereus in controlled by the transition state regulator AbrB, but not by the virulence regulator PlcR. Microbiology 155:922-931. 

Serra, D.O., Lücking, G., Weiland, F., Schulz, S., Gorg, A., Yantorno, O.M., Ehling-Schulz, M. (2008) Proteome approaches combined with Fourier transform infrared spectroscopy revealed a distinctive biofilm physiology in Bordetella pertussis. Proteomics 8:4995-5010. 




























Michaela Kreitmeier

PhD Student

Phone: +49 (8161) 71 3945
Fax: +49 (8161) 71 4492
E-mail: michaela.kreitmeier @ tum.de  



CV                                                                             
 

  • since 03/2017: PhD student at the Department of Microbiology, ZIEL, TU Munich. Research topic: "Characterisation of overlapping genes in the human pathogen Pseudomonas aeruginosa" .
  • 05/2016 - 11/2016 Master thesis at the Department of Microbiology, ZIEL, TU Munich, in the research group of Dr. Mareike Wenning with the title: "Analysis of AprA peptidase production in Pseudomonas - correlation between peptidase activity and trranscription of aprA-lipA operon genes".
  • 10/2011 - 11/2016: Studies in Molecular Biotechnology at the TU Munich































Christopher Maier

PhD Student

Phone: +49 (8161) 71 3859
Fax: +49 (8161) 71 4492
E-Mail: chris.maier @ tum.de


CV

                                
 



  • since May 2017: PdD Student at the Unit of Microbiology, ZIEL, TU Munich, in the group of Dr. Mareike Wenning. Research topic: "Production of heat-resistant peptidases by psychrotolerant Pseudomonas in raw milk"
  • October 2014 - September 2016: Studies in Biology at the Ludwig Maximilian´s University, Munich
  • November 2015 - April 2016: Master Thesis in the Research Group of Prof.  Dr. Kirsten Jung at the Unit of Microbiology, Ludwig Maximilian´s University, Munich. Research topic: "Acetyl-lysine uptake and metabolism in bacteria"
  • October 2010 - September 2013: Studies in Biology at the Ludwig-Maximilian´s University, Munich





























Jakob Schardt

PhD Student

Phone: +49 8161 71 3851
Fax: + 49 (8161) 71 4492
E-mail: jakob.schardt @ wzw.tum.de  



CV
 


  • since April 2014: PhD Student at the Unit of Microbiology, ZIEL, TU München, in the Research Group of Prof. Dr. Thilo M. Fuchs and of Dr. Stefanie Müller-Herbst studying the "Dynamic interplay between enteropathogens and host during gut colonization". Fellow Student of German Research Foundation (DFG) funded "Graduiertenkolleg 1482" (www.grk1482.de) investigating "Interface functions of the intestine between luminal factors and host signals".
  • August 2013 - January 2014: Master Thesis in the Research Group of Dr. Stefanie Müller-Herbst at the Unit of Microbiology, ZIEL, TU München. Research Topic: "Further characterization of the Nitrogen metabolism in Listeria monocytogenes"
  • October 2008 - March 2014: Studies in Molecular Biotechnology at the Technical University of Munich (TU München)

























Patrick Schiwek

Technical assistent

                                                         
Phone: +49 (81 61) 71 5566
Fax: +49 (81 61) 71 4492
E-mail: p.schiwek @ wzw.tum.de



CV

  • Seit Januar 1994: ZIEL, Abteilung Mikrobiologie; derzeit in der Arbeitsgruppe Dr.T.M. Fuchs. Zuständig als assistierender Betreuer für Praktikas der Studiengänge Biochemie/ Molekulare Biotechnologie und Ernährungswissenschaften
  • 1991-1993: Biologische Bundesanstalt für Land- und Forstwirtschaft in Grünbach, Inst. f. Resistenzgenetik (später BAZ: Bundesanstalt für Züchtungsforschung , Mitarbeit bei Prof. Dr. Gerhard Wenzel und  Frau Dr. Bärbel Foroughi-Wehr) im Forschungsprojekt:“Fusionshybriden der Kartoffel mit agronomisch wichtigen Eigenschaften: Gezielte somatische Kombination qualitativer und quantitativer Resistenzgene bei Genom und Plasmon Analyse der Hybriden auf ihr Resistenzniveau“.
  • Nach dem Abitur, Zivildienst und der Ausbildung zum Technischen Assistenten an den Landwirtschaftlichen Lehranstalten Landsberg/Lech, mit der  Fachrichtung Agrikulturchemie.






























Annemarie Siebert 

PhD Student

Phone:  +49 (8161) 71 3859
Fax: +49 (8161) 71 4492
E-mail: Annemarie.siebert @ tum.de  



CV

 


  • Since October 2017: PhD Student at the Department of Microbial Ecology, ZIEL, Technical University of Munich in the group of Dr. Mareike Wenning. Research topic: “Determination of farm specific influences on raw milk microbiota"
  • 10/2016 – 04/2017 Master’s Thesis at the Department of Technical Micobiology, Technical University of Munich. Research topic: “Identification and characterisation of Gushing associated proteins in sparkling wine”
  • 2014 – 2017 Studies in Biology at the Technical University of Munich
  • 2011 - 2014 Studies in Biology at the Johannes Gutenberg-University of Mainz

























Sonja Vanderhaeghen

Biochemistry 
PhD Student

Phone:  +49 (8161) 71 3945
Fax: +49 (8161) 71 4492
E-mail: Sonja.vanderhaeghen @ wzw.tum.de                   




CV
 

  • since November 2014:  PhD Student at the Research Group of Dr. Klaus Neuhaus at the Unit of Microbiology, ZIEL, TU Munich
  • January 2014 - August 2014: Master Thesis at the Department of Food Biotechnology, ETH Zürich; Topic: "Analysis of funtional properties of bifidobacteria and lactobacilli strains from feces and breast milk of mother-neonate pairs"
  • 2012 - 2014: Master Degree in "Biochemistry and molecular Biology" with focus on microbiology and molecular biology
  • 2009 - 2012: Bachelor Degree in "Biochemistry" at the University of Bayreuth
























Stefan Wichmann

PhD Student

Phone:  +49 (8161) 71 3945
Fax: +49 (8161) 71 4492
E-mail: stefan.wichmann @ tum.de




CV


  • since 11/2017 PhD Student at the Department of Microbiology at the Technical University of Munich (TUM). Research Topic: "Optimality and Evolution of the genetic code regarding overlapping genes".
  • 4/2017 - 7/2017 Highschool Physics Teacher at the Gisela-Gymnasium, Munich
  • 2016 - 2017  Bio-Physical Master Thesis in the Group of Prof. Dr. Erwin Frey, Research Topic: "May-Leonard Systems with asymmetric mobility".
  • 2014 - 2017 Master studies in Physics at the Ludwig-Maximilian-University (LMU) Munich
  • 2013 Bachelor Thesis in the Group of Prof. Dr. Jan von Delft. Research Topic: "Transport in a disordered quantum dot connected to one dimensional leads".
  • 2010 - 2014 Bachelor studies in Physics at the Ludwig-Maximilians-University (LMU), Munich.































Barbara Zehentner

PhD Student

Phone:  +49 (8161) 71 3945
Fax: +49 (8161) 71 4492
E-mail: Barbara.zehentner @ wzw.tum.de  



CV

 


  • since 01/2016 PhD student in the research group of Dr. Klaus Neuhaus at the Unit of Microbiology, ZIEL, TU München
  • 04/2015 – 11/2015 Master thesis in the research group of Dr. Klaus Neuhaus at the Unit of Microbiology, ZIEL, TU München, with the title "Expression and Function of overlapping ORFs in EHEC"
  • 10/2014 – 03/2015 Trainee at Eurofins Medigenomix, R&D Gensynthesis
  • 2010 – 2015 Studies in Molecular Biotechnology at TU München

























Aktuelles

Stellenausschreibung Doktorandenstelle
Doktorand(in) zum Thema "Molekulare Genetik überlappender Gene in Bakterien des Darmtraktes"

Masterarbeit zu Vergeben
Masters Project in Overlapping Genes Research Group

Paper
The Novel Anaerobiosis-Responsive Overlapping Antisense to the Annotated Gene ECs2385 of Escherichia coli O157:H7 Sakai (Mai 2018)

Paper
Thermal treatment of skim milk concentrates in a novel shear-heating device: Reduction of thermophilic spores and physical properties (Febr. 2018)

Paper
A novel short L-arginine responsive protein-coding gene (laoB) antiparallel overlapping to a CadC-like transcriptional regulator in Escherichia coli O157:H7 Sakai originated by overprinting (2018)

Paper
Comparison between Listeria sensu stricto and Listeria sensu lato strains identifies novel determinants involved in infection (2017)

Paper
Denkvoraussetzungen und weltanschauliche Überzeugungen in der Biologie (2017)

Paper
Differentiation of ncRNAs from small mRNAs in Escherichia coli O157:H7 EDL933 (EHEC) by combined RNAseq and RIBOseq-ryhB encodes the regulatory RNA Ryhb and a Peptide, RyhP. (2017)

Paper
Complete circular genome sequence and temperature independent adaptation to Anaerobiosis of Listeria weihenstephanensis DSM 24698 (2017)

Paper
Discovery of numerous novel small genes in the intergenic regions of the Escherichia coli O157:H7 Sakai Genome (2017)

Paper
Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk Is Mainly Induced by Psychrotolerant Spore-Forming Bacteria that often Originate from Recontamination (2017)

Paper
Transcriptional and translational regulation by RNA thermometers, riboswitches and the sRNA DsrA in Escherichia coli O157:H7 Sakai under combined cold and osmotic stress adaptation. (2016)

Paper
Comparative Bioinformatics and Experimental Analysis of the Intergenic Regulatory Regions of Bacillus cereus hbl and nhe Enterotoxin Operons and the Impact of CodY on Virulence Heterogeneity (Mai 2016)

Paper
Acidified nitrite inhibits proliferation of Listeria monocytogenes - Transcriptional analysis of a preservation method (März 2016)

Paper
Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC)

Paper
Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting (Dez. 2015).

Paper
Massive horizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe (Nov. 2015)